Antibody-based research, molecular assays, and biomarker investigations can help characterize disease-relevant mechanisms and generate evidence for therapeutic research.
The research question
Molecular evidence underpins every later decision: target selection, candidate characterization, and biomarker strategy. This capability focuses on generating molecular-level evidence that is fit for the purpose it will be used for.
Approach and methods
Methods, subject to confirmation
The following methods are discussed with each client and confirmed against scientific and operational requirements before any engagement:
- Custom antibody development — generation of research antibodies against defined targets.
- Antibody characterization — specificity, affinity, and performance evaluation.
- Immunoassay development — fit-for-purpose assays for target and biomarker measurement.
- Target expression and biomarker studies — where and how strongly a target is expressed, in relevant systems.
- Cell and tissue research — relevant cellular and tissue-based investigation.
Deliverables
What an engagement produces
- Characterized research antibodies or assay systems, as scoped.
- Target expression and biomarker study reports with methods and limitations.
- Assay performance documentation suitable for the intended use.
- Interpretation connecting molecular findings to the program question.
Scope and limitations
How work is delivered: Antibody-based and laboratory work is coordinated through participating research entities with the relevant facilities and expertise — including Antagene for antibody-based research. Each participating entity is a separate legal organization; AionWell does not present their facilities or results as its own. Scope, responsibilities, and data rights are defined contractually for each project. Research-use methods are not clinical diagnostics.
Relevant applications
Precision oncology target and biomarker programs, antibody therapeutic and ADC characterization, and biomarker support for radiopharmaceutical research.
Have a target or biomarker question?
Tell us what you need to measure, and the decision it will inform.